Manioc : Portail | resultats 1 - 16 pour la recherche: Verdoni, Dominique

Mémoire pour le chef de brigade Magloire Pélage et pour les habitants de la Guadeloupe chargés par cette colonie de l'administration provisoire après le départ du capitaine général dans le mois de brumaire an X T.2
Auteur(s) : Frasans, Hippolyte de (1768-18..) Langloys, Jean-Thomas (1746-1804)
Année de publication :

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La France et ses colonies. Tome 1: En France
Auteur(s) : Reclus, Onésime (1837-1916)
Année de publication :

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Mémoire pour le chef de Brigade Magloire Pélage et pour les habitants de la Guadeloupe. Tome second
Auteur(s) : Frasans, Hippolyte de (1768-18..) Langloys, Jean-Thomas (1746-1804)
Année de publication :

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Incidence, medical and socio-behavioural predictors of psychiatric events in an 11-year follow-up of HIV-infected patients on antiretroviral therapy.
Auteur(s) : Protopopescu, Camelia Raffi, François Brunet-François, Cécile Salmon, Dominique Verdon, Renaud Reboud, Philippe Carrieri, Maria Patrizia Leport, Catherine
Auteurs secondaires : Aix Marseille Université (AMU) Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM) ; Institut de Recherche pour le Développement (IRD) - Aix Marseille Université (AMU) - ORS PACA - Institut National de la Santé et de la Recherche Médicale (INSERM) Maladies infectieuses et tropicales Service de médecine interne et centre de référence des maladies rares [CHU Cochin] ; CHU Cochin [AP-HP] - Assistance publique - Hôpitaux de Paris (AP-HP) Service des maladies infectieuses et tropicales ; CHU Caen Epidémiologie et Biostatistique [Bordeaux] ; Université Bordeaux Segalen - Bordeaux 2 - Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED) - Institut National de la Santé et de la Recherche Médicale (INSERM) Modèles et méthodes de l'évaluation thérapeutique des maladies chroniques ; Université Paris Diderot - Paris 7 (UPD7) - Institut National de la Santé et de la Recherche Médicale (INSERM) Troubles du comportement alimentaire de l'adolescent (UMR_S 669) ; Université Paris Descartes - Paris 5 (UPD5) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Université Paris-Sud - Paris 11 (UP11)

Éditeur(s) : HAL CCSD International Medical Press
Résumé : International audience
BACKGROUND: Psychiatric disorders are relatively common among HIV-infected patients. However, there are few studies about their potential risk factors. This analysis aimed to measure the incidence of severe psychiatric events (PE) among patients receiving combination antiretroviral therapy (cART) of the French APROCO-COPILOTE (ANRS CO8) cohort, and to identify the medical and socio-behavioural correlates of their first episode of depression, suicide or suicide attempt (D/S/SA). METHODS: APROCO-COPILOTE is a cohort of patients started on a protease inhibitor regimen between 1997 and 1999, with prospective medical standardized records and self-administered questionnaires collecting socio-demographic and socio-behavioural data. This analysis included all 11-year follow-up visits for 1,095 patients having completed baseline self-administered questionnaires. A proportional hazard Cox model was used to identify the correlates of a first D/S/SA event. RESULTS: The overall prevalence of severe PE remained low: 50 patients experienced 67 events (incidence rate [95% CI] =1.04 [0.82, 1.32] per 100 person-years). Depression (n=16), suicides (n=5) and suicide attempts (n=14) were the most frequently diagnosed PE (0.54 [0.39, 0.76] per 100 person-years) among 25 patients. Multivariate results showed that unemployment, unstable housing, detectable viral load and smoking more than 20 cigarettes/day were independently associated with D/S/SA. CONCLUSIONS: Although the incidence of severe PE remained relatively low among the patients of APROCO-COPILOTE cohort, this study's results underline a clinically important problem in HIV-infected patients receiving cART. Furthermore, our findings not only emphasize the importance of comprehensive care, especially for socially vulnerable patients, but may also help future studies designed to assess the effectiveness of interventions in reducing the risk of PE during cART.
ISSN: 1359-6535

hal-00875183
https://hal.archives-ouvertes.fr/hal-00875183
DOI : 10.3851/IMP2102
PUBMED : 22544079

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